Epithelial mesenchymal transition (EMT)

This project is focusing on the role of EMT in COPD and its role in lung cancer development and progression using in vitro primary bronchial epithelial cell (PBEC) cultures from COPD/smokers and lung cancer patients and also bronchial biopsies from COPD patients and surgically resected tissue from lung cancer patients for markers of EMT and effect of drugs (inhaled corticosteroids and azithromycin) and vitamin-D on EMT, spontaneous and before and after stimulation (TGF-B1).

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