International Collaboration on Cardiovascular Disease Risk from Childhood to Adulthood
Very few studies internationally have the capacity to examine the contribution of childhood factors to the risk of cardiovascular disease in adulthood. Those that do have extensive measures of physical and lifestyle characteristics at multiple time points and large numbers of participants followed since childhood. This international collaboration has been established to pool data from three such studies: the Childhood Determinants of Adult Health Study conducted at Menzies, the Cardiovascular Risk in Young Finns Study from Finland, and the Bogalusa Heart Study from the USA. By pooling data, we have greater ability to examine rare outcomes and, when findings are consistent across the three cohorts, more confidence in the results.
Our first collaborative project was completed in 2007. It investigated the utility of two currently recommended paediatric dyslipidaemia classifications (for blood cholesterol and triglycerides) in predicting dyslipidaemia in adulthood. The study found that the two classifications had different strengths; one better predicted high density lipoprotein cholesterol and the other better predicted total and low density lipoprotein cholesterol and triglycerides. These findings will be very helpful when existing paediatric dyslipidaemia guidelines are updated.
This project is a participant based study
- Professor Terry Dwyer (Honorary Research Professor)
- Dr Costan Magnussen (PhD Student)
- Professor Alison Venn
- Professor Gerald Berenson
- Professor Olli Raitakari - University of Turku