Neonatal Respiratory Group

The Neonatal Respiratory Group aims to understand the pathogenesis and pathophysiology of neonatal respiratory disease, develop and evaluate therapies for infants with respiratory failure, and improve the ventilatory and supportive care provided to such infants.

The research activities of the group have 4 sub-themes:

Sub-theme 1. Innovation in surfactant therapy

Exogenous surfactant therapy has been a cornerstone of treatment for preterm infants for two decades. The broad objective of this research theme is to extend the therapeutic possibilities for surfactant in neonates with lung disease.

Sub-theme 2. Optimisation of lung volume during mechanical ventilation

In providing ventilatory support to babies with respiratory failure, clinicians face the difficult task of applying ventilation in such a way as to avoid atelectasis and overdistension without having a bedside measure of absolute lung volume. The broad objective of this research theme is to find methods to optimise lung volume during both conventional mechanical ventilation (CMV) and high frequency oscillatory ventilation (HFOV), using new technologies that can be applied at the bedside.

Sub-theme 3. Neonatal oximetry and oxygen therapy

This theme has the broad objective of delivering oxygen more effectively and efficiently to hypoxic infants.

Sub-theme 4. Evidence-based medicine in neonatology

This theme has the broad objective of assembling evidence regarding neonatal respiratory management, with a focus on therapies of current interest to the Menzies Neonatal Respiratory Group.

Parent Theme

Research Projects

Related Funding Bodies

Staff

Team Members

  • Professor Peter Dargaville (Honorary Research Fellow)
  • Dr Tony De Paoli
  • Dr Angela Gerber
  • Dr Katharine Squires

Local Collaborators

  • Associate Professor Tim Gale
  • Mr Deip Khong (Honours Student)

External Collaborators

  • Professor Peter Davis, Royal Women's Hospital, Melbourne
  • Professor John Carlin, Murdoch Children's Research Institute
  • Dr David Tingay, Royal Children's Hospital, Melbourne
  • Dr Raffaele Dellacá, Politecnico di Milano, Milan, Italy
  • Dr Peter Rimensberger, University of Geneva, Switzerland
  • Professor Inéz Frerichs